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Hirohisa Tsujinoue Selected Research

Carcinogenesis

6/2004Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice.
9/2003The copper-chelating agent, trientine, attenuates liver enzyme-altered preneoplastic lesions in rats by angiogenesis suppression.
7/2003Extracellular matrix remodeling may predominate over hepatocyte injury in hepatocellular carcinoma development.
7/2002Inhibition of renin-angiotensin system attenuates liver enzyme-altered preneoplastic lesions and fibrosis development in rats.

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Hirohisa Tsujinoue Research Topics

Disease

7Neoplasms (Cancer)
07/2004 - 04/2002
5Hepatocellular Carcinoma (Hepatoma)
07/2004 - 04/2002
4Liver Cirrhosis (Hepatic Cirrhosis)
02/2005 - 07/2002
4Fibrosis (Cirrhosis)
02/2005 - 07/2002
4Carcinogenesis
06/2004 - 07/2002
1Colitis
11/2006
1Neoplasm Metastasis (Metastasis)
06/2004

Drug/Important Bio-Agent (IBA)

5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2004 - 04/2002
4PerindoprilFDA LinkGeneric
02/2005 - 06/2002
4Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
02/2005 - 06/2002
4Messenger RNA (mRNA)IBA
06/2003 - 04/2002
3Tissue Inhibitor of Metalloproteinase-1IBA
09/2003 - 10/2002
2Interferon-betaIBA
02/2005 - 12/2003
2Hydroxyproline (4 Hydroxyproline)IBA
02/2005 - 07/2002
2Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
06/2004 - 12/2003
2CDAA (Randox)IBA
07/2003 - 07/2002
2Amino AcidsFDA Link
07/2003 - 07/2002
2Choline (Choline Chloride)IBA
07/2003 - 07/2002
2EnzymesIBA
07/2003 - 07/2002
2Matrix Metalloproteinases (MMPs)IBA
06/2003 - 10/2002
1Neuraminidase (Sialidase)IBA
11/2006
1Oseltamivir (Tamiflu)FDA Link
11/2006
1Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
07/2004
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
07/2004
1Trientine (Trien)FDA Link
09/2003
1Chelating AgentsIBA
09/2003
1CopperIBA
09/2003
1Protein Kinase CIBA
09/2003
1Angiotensin IIIBA
09/2003
1saiko-keishi-to (TJ10)IBA
07/2003
1Plant ExtractsIBA
07/2003
1Biomarkers (Surrogate Marker)IBA
07/2003
1shosaiko-to (TJ9)IBA
07/2003
1Glutathione Transferase (Glutathione S-Transferase)IBA
07/2003
1Caspase 3 (Caspase-3)IBA
10/2002
1ProcollagenIBA
10/2002
1CollagenIBA
07/2002
1Diethylnitrosamine (N-Nitrosodiethylamine)IBA
07/2002
1Tetracycline (Achromycin)FDA LinkGeneric
06/2002
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
06/2002
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
04/2002
1Monoclonal AntibodiesIBA
04/2002

Therapy/Procedure

1Therapeutics
02/2005
1Transplantation
07/2004